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1.
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (1): 67-73
in English | IMEMR | ID: emr-185742

ABSTRACT

The present study investigates anti-diabetic and anti-oxidant potentials of the aerial parts of Aerva javanica and seeds of Linum ustitatissimum. Our results revealed that maximum antioxidant activity was found in hexane fractions of both plants. Linum ustitatissimum recorded maximum antioxidant value of 15.77mmol/L while Aerva javanica had antioxidant activity of 16.07mmol/L. Anti-diabetic activities were also evaluated using normal rats, induced diabetic [untreated] rats and treated diabetic rats. Aerva javanica revealed a significant potential in decreasing blood glucose level to 77.08mg/dl and body weight 76.30mg/kg while Linum ustitatissimum reduced blood glucose level to 84.20mg/dl and body weight 83.090mg/kg. From these results it can be concluded that both plants possesses antidiabetic and anti-oxidant activity


Subject(s)
Animals, Laboratory , Phytotherapy , Amaranthaceae , Plant Components, Aerial , Antioxidants , Hypoglycemic Agents , Diabetes Mellitus, Experimental/drug therapy , Rats
2.
Pakistan Journal of Pharmaceutical Sciences. 2016; 29 (3): 861-868
in English | IMEMR | ID: emr-179555

ABSTRACT

The present study reveals antimicrobial potentials and phytochemical analysis of A. javanica and L. ustitatissimum. Phytochemical analysis indicated that the tested plants contained a substantial amount of flavonoids, terpenoids and steroids while saponins and tannins were absent in L. ustitatissimum, however, tannins were present in A. javanica. L. ustitatissimum contained maximum total phenolic content of 166.36mg/g in methylated spirit fraction while its ethyl acetate fraction contained highest quantity of flavonoids 27.6mg/g in case of Aerva javanica. Antimicrobial potentials of the subject plants revealed that L. ustitatissimum had maximum antibacterial activity [MIC=4.33microg/ml] while A. javanica was most effective against fungal strains [MIC=2.66 microg/ml]

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